Past Calls

We Are Hiring

We are looking to recruit a word-class team to i3S, one of Portugal’s top science institutes, in the newly created ERA Chair group – NCBio – headed by Dr. Matthew Holt.

  • PhD student fellowship
  • Junior Researcher

By joining the project NCBio: Unlocking Excellence In Research And Innovation In Neurobiology And Neurological Disorders you will have the oportunity to study aspects of inhibitory synapse formation and function, using a variety of cutting-edge techniques, ranging from proteomics through advanced genetics to electrophysiology.

Key Dates

Junior Researcher 
Application deadline: 18th August 2023

Estimated start date: During 2023

PhD student fellowship
Application deadline: 28th August 2023

Estimated start date: September 2023

For further information, please contact us at mholt@i3s.up.pt

Junior Researcher

We’re looking for candidates with a PhD in neuroscience and a solid track record of achievements (1st author publications, conference talks, posters etc), skilled in advanced molecular biology and protein biochemistry techniques and experience in tissue culture techniques.

  • General requirements
  • Highly motivated with a Ph.D. degree in neuroscience and a solid track record of achievements (1st author publications, conference talks, posters etc).
  • Skilled in advanced molecular biology and protein biochemistry techniques (gene design and cloning, Western blot, immunohistochemistry, RNA isolation, RT-qPCR, transcriptomics, CRISPRCas9 systems, proteomics, immunoprecipitation, data analysis tools).
  • Experience in tissue culture techniques: establishment and maintenance of cell lines, preparation of primary cortical neuron and astrocyte cultures from mice and rats, genetic manipulation (transfection/transduction).
  • Knowledge of fluorescence microscopy (including confocal).
  • Ability to work independently, but also capable of collaborative work.
  • Fluent in written and spoken English.
  • Experience in mouse work (in utero electroporation, stereotaxic injections, perfusion, sectioning [vibratome and cryostat] and immunohistochemistry) is desirable, but not essential.
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Job Description

PhD student fellowship

We are recruiting a Ph.D. student to join the team and work on a project aimed at identifying astrocyte secreted factors that differentially modulate synapse assembly. Candidates should meet the criteria of “Statute of the Scientific Research Grant Holder”, approved by Law no. 40/2004, of 18 August and republished by DL 123/2019.

Admission requirements include:

  • General requirements
  • Must have obtained a recent M.Sc. in neuroscience. Applicants with a M.Sc. in molecular biology, biochemistry or cell biology with a knowledge of synapse biology will also be considered.
  • Must be eligible for admittance to an approved Doctoral School at the University of Porto (and be able to provide supporting documents).
  • Must be within the top 10% of year group and committed to a career in top-class science: you are highly motivated and goal-directed.
  • Hands-on lab experience (M.Sc. thesis, summer internships etc) is an advantage
  • Capable of working independently and as part of a team.
  • Fluent in written and spoken English.
APPLY NOW
Job Description